Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7445187 | 0.86 | GAA (0.41) | MAPTNPSR1ALDH1A1L3MBTL1CYP4F2 | |
| SCHEMBL7437999 | 0.84 | MAPT (0.38) | MAPTNPSR1ALDH1A1L3MBTL1CYP4F2 | |
| SCHEMBL7434611 | 0.84 | MAPT (0.41) | MAPTNPSR1ALDH1A1L3MBTL1CYP4F2 | |
| SCHEMBL3525418 | 0.83 | CA12 (0.42) | MAPTNPSR1ALDH1A1L3MBTL1CYP4F2 | |
| SCHEMBL7431988 | 0.83 | MAPT (0.40) | MAPTNPSR1ALDH1A1L3MBTL1CYP4F2 | |
| SCHEMBL4159695 | 0.83 | CYP3A4 (0.40) | MAPTNPSR1ALDH1A1L3MBTL1CYP4F2 | |
| SCHEMBL29186867 | 0.79 | TSHR (0.45) | MAPTNPSR1ALDH1A1L3MBTL1CYP4F2 | |
| SCHEMBL5524661 | 0.78 | MAPT (0.47) | MAPTNPSR1ALDH1A1L3MBTL1CYP4F2 | |
| SCHEMBL13612612 | 0.77 | MAPT (0.42) | MAPTNPSR1ALDH1A1L3MBTL1CYP4F2 | |
| Hydrochloric Acid SCHEMBL5524658 | 0.77 | MAPT (0.46) | MAPTNPSR1ALDH1A1L3MBTL1CYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |