Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 20/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 14/20 | 0.54 |
| ▸ | ITGB6 | P18564 | 6/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4530325 | 0.76 | ITGAV (0.43) | ITGAVITGB3ITGB6 | |
| SCHEMBL21715684 | 0.74 | ITGAV (0.40) | ITGAVITGB3ITGB6 | |
| SCHEMBL21715687 | 0.73 | ITGAV (0.39) | ITGAVITGB3ITGB6 | |
| SCHEMBL7564709 | 0.72 | ITGAV (0.76) | ITGAVITGB3ITGB6 | |
| SCHEMBL31085337 | 0.72 | ITGAV (0.82) | ITGAVITGB3ITGB6 | |
| SCHEMBL21766819 | 0.71 | ITGAV (0.60) | ITGAVITGB3ITGB6 | |
| SCHEMBL23292848 | 0.71 | ITGAV (0.44) | ITGAVITGB3ITGB6 | |
| SCHEMBL21780649 | 0.71 | ITGAV (0.60) | ITGAVITGB3ITGB6 | |
| SCHEMBL5301992 | 0.71 | ITGAV (0.78) | ITGAVITGB3ITGB6 | |
| SCHEMBL5301988 | 0.71 | ITGAV (0.78) | ITGAVITGB3ITGB6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3813818-A1 | AMINO ACID COMPOUNDS WITH UNBRANCHED LINKERS AND METHODS OF USE | Pliant Therapeutics, Inc. (US) | 2021-05-05 | — | — | EP | disclosed |
| EP-1187592-A4 | ALPHA V INTEGRIN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 2002-11-06 | — | — | EP | disclosed |
| US-6410526-B1 | BONE DISORDERS; RESTENOSIS; VISION DISORDERS; ANTICHOLESTEROL AGENTS; ANTICANCER, ANTITUMOR AGENTS | MERCK & CO., INC. | 2002-06-25 | — | — | US | disclosed |
| EP-1187592-A2 | ALPHA V INTEGRIN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 2002-03-20 | — | — | EP | disclosed |
| WO-2000072801-A2 | ALPHA V INTEGRIN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 2000-12-07 | — | — | WO | disclosed |