Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 19/20 | 0.60 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.48 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7433005 | 0.89 | PDE5A (0.63) | PDE5ATBXAS1PDE3BPDE3APTGS1 | |
| SCHEMBL7433246 | 0.88 | PDE5A (0.60) | PDE5ATBXAS1PDE3BPDE3APTGS1 | |
| SCHEMBL7280235 | 0.88 | PDE5A (0.64) | PDE5ATBXAS1PDE3BPDE3APTGS1 | |
| SCHEMBL7280632 | 0.88 | PDE5A (0.60) | PDE5ATBXAS1PDE3BPDE3APTGS1 | |
| SCHEMBL7277444 | 0.88 | PDE5A (0.66) | PDE5ATBXAS1PDE3BPDE3APTGS1 | |
| Hydrochloric Acid SCHEMBL7287960 | 0.87 | PDE5A (0.64) | PDE5ATBXAS1PDE3BPDE3APTGS1 | |
| Hydrochloric Acid SCHEMBL7277419 | 0.87 | PDE5A (0.66) | PDE5ATBXAS1PDE3BPDE3APTGS1 | |
| SCHEMBL7280025 | 0.86 | PDE5A (0.80) | PDE5ATBXAS1PDE3BPDE3APTGS1 | |
| SCHEMBL7444562 | 0.84 | PDE5A (0.67) | PDE5ATBXAS1PDE3BPDE3APTGS1 | |
| SCHEMBL7289821 | 0.84 | PDE5A (0.53) | PDE5ATBXAS1PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579496-A1 | 4-Aminoquinazoline derivatives, and their use as medicine | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-01-19 | — | — | EP | disclosed |