Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.63 |
| ▸ | GFER | P55789 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28070206 | 0.81 | NR4A2 (0.68) | ALDH1A1LMNANR4A2SMN1; SMN2KMT2A | |
| SCHEMBL7267001 | 0.79 | SMN1; SMN2 (0.57) | GAAGFERMAPTALDH1A1LMNA | |
| SCHEMBL16979075 | 0.78 | KMT2A (0.75) | ALDH1A1LMNANR4A2SMN1; SMN2KMT2A | |
| SCHEMBL980722 | 0.77 | GAA (0.56) | GAAGFERMAPTALDH1A1LMNA | |
| SCHEMBL14159256 | 0.77 | NR4A2 (0.71) | ALDH1A1LMNANR4A2SMN1; SMN2KMT2A | |
| SCHEMBL30373303 | 0.76 | NR4A2 (0.69) | MAPTALDH1A1LMNANR4A2SMN1; SMN2 | |
| SCHEMBL2429622 | 0.76 | NR4A2 (0.69) | MAPTALDH1A1LMNANR4A2SMN1; SMN2 | |
| SCHEMBL13564517 | 0.76 | NR4A2 (0.69) | MAPTALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL3058391 | 0.74 | NR4A2 (0.68) | GAAALDH1A1LMNANR4A2SMN1; SMN2 | |
| SCHEMBL1538812 | 0.73 | NR4A2 (0.66) | ALDH1A1LMNANR4A2SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5492919-A | IRRITABLE BOWEL DISORDER | SMITHKLINE BEECHAM P.L.C. (GB) | 1996-02-20 | — | — | US | disclosed |
| WO-1993002677-A1 | 5-HT4 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1993-02-18 | — | — | WO | disclosed |