Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WHR1 | P49842 | 2/20 | 0.60 |
| ▸ | KMT5A | Q9NQR1 | 8/20 | 0.56 |
| ▸ | PDE5A | O76074 | 8/20 | 0.52 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.52 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.52 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.46 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7406562 | 0.87 | PDE5A (0.53) | KMT5APDE5ATBXAS1PDE3BPDE3A | |
| Hydrochloric Acid SCHEMBL7437141 | 0.86 | PDE5A (0.54) | KMT5APDE5ATBXAS1PDE3BPDE3A | |
| SCHEMBL7433363 | 0.85 | PDE5A (0.71) | KMT5APDE5ATBXAS1PDE3BPDE3A | |
| SCHEMBL7286638 | 0.82 | PDE5A (0.49) | KMT5APDE5ATBXAS1PDE3BPDE3A | |
| SCHEMBL7431779 | 0.82 | PDE5A (0.54) | PDE5ATBXAS1PDE3BPDE3A | |
| SCHEMBL7436401 | 0.82 | PDE5A (0.68) | PDE5ATBXAS1PDE3BPDE3A | |
| SCHEMBL7280247 | 0.81 | PDE5A (0.60) | PDE5ATBXAS1PDE3BPDE3A | |
| SCHEMBL7437955 | 0.81 | PDE5A (0.53) | PDE5ATBXAS1PDE3BPDE3A | |
| SCHEMBL7434941 | 0.81 | PDE5A (0.53) | PDE5ATBXAS1PDE3BPDE3A | |
| SCHEMBL7438332 | 0.81 | PDE5A (0.53) | PDE5ATBXAS1PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579496-A1 | 4-Aminoquinazoline derivatives, and their use as medicine | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-01-19 | — | — | EP | disclosed |