Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 20/20 | 0.59 |
| ▸ | F10 | P00742 | 2/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.51 |
| ▸ | CTRC | Q99895 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7436286 | 1.00 | F2 (0.59) | F2F10PRSS2CTRC | |
| SCHEMBL7452093 | 0.88 | F2 (0.67) | F2F10PRSS2CTRC | |
| SCHEMBL7452099 | 0.88 | F2 (0.67) | F2F10PRSS2CTRC | |
| SCHEMBL7442488 | 0.87 | F2 (0.58) | F2F10PRSS2CTRC | |
| SCHEMBL7442482 | 0.87 | F2 (0.58) | F2F10PRSS2CTRC | |
| SCHEMBL7446819 | 0.83 | F2 (0.85) | F2F10PRSS2 | |
| Hydrochloric Acid SCHEMBL7446815 | 0.82 | F2 (0.83) | F2F10PRSS2 | |
| SCHEMBL8702730 | 0.80 | F2 (0.36) | F2 | |
| Hydrochloric Acid SCHEMBL7604311 | 0.79 | F2 (0.64) | F2F10PRSS2CTRC | |
| SCHEMBL7440276 | 0.76 | F2 (0.77) | F2F10PRSS2CTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0859607-B1 | GUANIDINO PROTEASE INHIBITORS | DIMENSIONAL PHARM INC (US) | 2002-12-18 | — | — | EP | claimed |
| EP-0859607-A4 | GUANIDINO PROTEASE INHIBITORS | DIMENSIONAL PHARM INC (US) | 1999-05-06 | — | — | EP | claimed |
| EP-0859607-A1 | GUANIDINO PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1998-08-26 | — | — | EP | claimed |
| WO-1997011693-A1 | GUANIDINO PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1997-04-03 | — | — | WO | claimed |