Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 20/20 | 0.76 |
| ▸ | PDE4A | P27815 | 1/20 | 0.71 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.71 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7440927 | 0.91 | PDE4B (0.76) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7441242 | 0.91 | PDE4B (0.90) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7431229 | 0.86 | PDE4B (0.76) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7437810 | 0.86 | PDE4B (0.89) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7443177 | 0.85 | PDE4B (0.89) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3170704 | 0.84 | PDE4B (0.66) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7437791 | 0.83 | PDE4B (0.89) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL8328029 | 0.83 | PDE4B (1.00) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7445013 | 0.83 | PDE4B (0.71) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL8327025 | 0.82 | PDE4B (1.00) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696276-A1 | N-ACYL SUBSTITUTED PHENYL PIPERIDINES AS BRONCHODILATORS AND ANTI-INFLAMMATORY AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-02-14 | — | — | EP | claimed |
| US-5459151-A | N-acyl substituted phenyl piperidines as bronchodilators and antiinflammatory agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-10-17 | — | — | US | claimed |
| WO-1994025437-A1 | N-ACYL SUBSTITUTED PHENYL PIPERIDINES AS BRONCHODILATORS AND ANTI-INFLAMMATORY AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-11-10 | — | — | WO | claimed |
| EP-0696276-A1 | N-ACYL SUBSTITUTED PHENYL PIPERIDINES AS BRONCHODILATORS AND ANTI-INFLAMMATORY AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-02-14 | — | — | EP | disclosed |
| US-5459151-A | N-acyl substituted phenyl piperidines as bronchodilators and antiinflammatory agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-10-17 | — | — | US | disclosed |
| WO-1994025437-A1 | N-ACYL SUBSTITUTED PHENYL PIPERIDINES AS BRONCHODILATORS AND ANTI-INFLAMMATORY AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-11-10 | — | — | WO | disclosed |