Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 20/20 | 0.89 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7440134 | 0.92 | ELANE (0.86) | ELANE | |
| SCHEMBL7445407 | 0.92 | ELANE (0.89) | ELANE | |
| SCHEMBL7443449 | 0.90 | ELANE (0.86) | ELANE | |
| SCHEMBL9011645 | 0.90 | ELANE (0.89) | ELANE | |
| SCHEMBL7450541 | 0.89 | ELANE (0.89) | ELANE | |
| SCHEMBL7447365 | 0.88 | ELANE (0.85) | ELANE | |
| SCHEMBL7500635 | 0.88 | ELANE (0.85) | ELANE | |
| SCHEMBL7447265 | 0.87 | ELANE (0.83) | ELANE | |
| SCHEMBL5076881 | 0.87 | ELANE (1.00) | ELANE | |
| SCHEMBL7431953 | 0.86 | ELANE (0.71) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521179-A | Heterocyclic amides | ZENECA LIMITED (GB) | 1996-05-28 | — | — | US | disclosed |
| WO-1993021212-A1 | LACTAM DIPEPTIDES HAVING HLE INHIBITING ACTIVITY | ZENECA LIMITED (GB) | 1993-10-28 | — | — | WO | disclosed |