Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL236357 | 0.89 | CES1 (0.47) | CES1KCNN4ENPP2PTPN1NR1H2 | |
| SCHEMBL236358 | 0.89 | CES1 (0.47) | CES1KCNN4ENPP2PTPN1NR1H2 | |
| SCHEMBL246914 | 0.89 | CES1 (0.47) | CES1KCNN4ENPP2PTPN1NR1H2 | |
| Hydrochloric Acid SCHEMBL8829227 | 0.87 | CES1 (0.46) | CES1KCNN4ENPP2PTPN1NR1H2 | |
| Hydrochloric Acid SCHEMBL5595770 | 0.87 | CES1 (0.46) | CES1KCNN4ENPP2PTPN1NR1H2 | |
| Hydrochloric Acid SCHEMBL4926039 | 0.87 | CES1 (0.46) | CES1KCNN4ENPP2PTPN1NR1H2 | |
| SCHEMBL464445 | 0.85 | CES1 (0.44) | CES1KCNN4ENPP2PTPN1NR1H2 | |
| SCHEMBL12341938 | 0.85 | CES1 (0.44) | CES1KCNN4ENPP2PTPN1NR1H2 | |
| SCHEMBL686435 | 0.85 | CES1 (0.44) | CES1KCNN4ENPP2PTPN1NR1H2 | |
| SCHEMBL527656 | 0.84 | CES1 (0.43) | CES1KCNN4ENPP2PTPN1NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5196437-A | Macrolide | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1993-03-23 | — | — | US | claimed |