Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7441978 | 0.88 | ACE (0.81) | ACE | |
| SCHEMBL7444467 | 0.88 | ACE (0.81) | ACE | |
| SCHEMBL7431829 | 0.88 | ACE (0.81) | ACE | |
| SCHEMBL7324587 | 0.84 | ACE (0.78) | ACE | |
| SCHEMBL7324885 | 0.84 | ACE (0.76) | ACE | |
| SCHEMBL8447572 | 0.83 | ACE (0.74) | ACE | |
| SCHEMBL7441105 | 0.83 | ACE (1.00) | ACE | |
| SCHEMBL7273504 | 0.82 | ACE (0.69) | ACE | |
| SCHEMBL7327419 | 0.81 | ACE (1.00) | ACE | |
| SCHEMBL7325439 | 0.81 | MME (0.73) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5262436-A | Administering; enzyme inhibitor | SCHERING CORPORATION (US) | 1993-11-16 | — | — | US | disclosed |
| US-5061710-A | Atrial natriuretic factors | SCHERING CORPORATION (US) | 1991-10-29 | — | — | US | disclosed |
| US-4929641-A | DIURETICS, ANGIOTENSIN CONVERTING ENZYMES | SCHERING CORPORATION (US) | 1990-05-29 | — | — | US | disclosed |
| US-4801609-A | Mercapto-acylamino acid antihypertensives | SCHERING CORPORATION (US) | 1989-01-31 | — | — | US | disclosed |