Sugi Predict

Sugi Predict / Compounds / SCHEMBL743718

SCHEMBL743718

SCHEMBL743718

CC(C)(CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)N1CCc2nc(C(=O)C3(N)CCCC3NC(=O)c3cc4cc(Cl)ccc4[nH]3)sc2C1

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ F10 P00742 20/20 0.48
▸ F2 P00734 4/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL742542 0.89 F10 (0.49) F10F2
Hydrochloric Acid SCHEMBL743409 0.87 F10 (0.57) F10F2
SCHEMBL4093877 0.87 F10 (0.66) F10F2
SCHEMBL4093881 0.87 F10 (0.66) F10F2
Hydrochloric Acid SCHEMBL743631 0.84 F10 (0.55) F10F2
Hydrochloric Acid SCHEMBL1504126 0.84 F10 (0.67) F10F2
SCHEMBL13379476 0.84 F10 (0.67) F10F2
SCHEMBL4097525 0.83 F10 (0.63) F10F2
SCHEMBL1503996 0.83 F10 (0.63) F10F2
SCHEMBL1503998 0.83 F10 (0.63) F10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2431370-B1 Monoacylated 1,2-diaminocycloalkanes DAIICHI SANKYO CO LTD (JP) 2013-06-19 — — EP disclosed
EP-2431370-A1 Monoacylated 1,2-diaminocycloalkanes DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2012-03-21 — — EP disclosed
US-7935824-B2 Ethylenediamine derivatives DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2011-05-03 — — US disclosed