Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 20/20 | 0.78 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.78 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.78 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.78 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.67 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7277032 | 0.89 | PDE5A (0.76) | PDE5ATBXAS1PDE3BPDE3APTGS1 | |
| SCHEMBL7279919 | 0.88 | PDE5A (0.71) | PDE5ATBXAS1PDE3BPDE3APTGS1 | |
| SCHEMBL7277505 | 0.88 | PDE5A (0.71) | PDE5ATBXAS1PDE3BPDE3APTGS1 | |
| SCHEMBL7277711 | 0.88 | PDE5A (1.00) | PDE5ATBXAS1PDE3BPDE3APTGS1 | |
| Hydrochloric Acid SCHEMBL7286149 | 0.87 | PDE5A (0.70) | PDE5ATBXAS1PDE3BPDE3APTGS1 | |
| Hydrochloric Acid SCHEMBL7280487 | 0.87 | PDE5A (1.00) | PDE5ATBXAS1PDE3BPDE3APTGS1 | |
| SCHEMBL7435225 | 0.86 | PDE5A (0.74) | PDE5ATBXAS1PDE3BPDE3APTGS1 | |
| SCHEMBL7431839 | 0.83 | PDE5A (0.77) | PDE5ATBXAS1PDE3BPDE3APTGS1 | |
| SCHEMBL7287473 | 0.83 | PDE5A (1.00) | PDE5ATBXAS1PDE3BPDE3APTGS1 | |
| SCHEMBL715585 | 0.82 | PDE5A (1.00) | PDE5ATBXAS1PDE3BPDE3APTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579496-A1 | 4-Aminoquinazoline derivatives, and their use as medicine | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-01-19 | — | — | EP | claimed |