Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | USP5 | P45974 | 1/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1518689 | 0.96 | KMT2A (0.52) | KMT2AMEN1PKMALDH1A1MAPT | |
| SCHEMBL1518835 | 0.96 | MEN1 (0.50) | KMT2AMEN1PKMALDH1A1GAA | |
| SCHEMBL2419999 | 0.91 | KMT2A (0.49) | KMT2AMEN1PKMALDH1A1GAA | |
| SCHEMBL2422148 | 0.90 | KMT2A (0.50) | KMT2AMEN1ALDH1A1MAPTMAPK9 | |
| SCHEMBL2420432 | 0.90 | KMT2A (0.53) | KMT2AMEN1PKMALDH1A1GAA | |
| SCHEMBL2425542 | 0.89 | KMT2A (0.49) | KMT2AMEN1PKMALDH1A1GAA | |
| SCHEMBL6432690 | 0.88 | MEN1 (0.52) | KMT2AMEN1PKMALDH1A1NPC1 | |
| SCHEMBL2421181 | 0.87 | MEN1 (0.49) | KMT2AMEN1ALDH1A1MAPTMAPK9 | |
| SCHEMBL2427809 | 0.87 | KMT2A (0.50) | KMT2AMEN1ALDH1A1GAAMAPT | |
| SCHEMBL2422541 | 0.87 | KMT2A (0.56) | KMT2AMEN1PKMALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218374-A1 | PHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES | Applied Research Systems ARS Holding N.V. (AN) | 2002-07-03 | — | — | EP | claimed |
| WO-2001023378-A1 | PHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-04-05 | — | — | WO | claimed |