SCHEMBL7437768

SCHEMBL7437768

CC(C)C(Cl)B1OC(C)(C)C(C)(C)O1

nearest known ligand 0.50

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 3/20 0.50
LAP3 P28838 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10937279 0.78 ANPEP (0.55) ANPEPLAP3
SCHEMBL10940277 0.77 ANPEP (0.43) ANPEPLAP3
SCHEMBL3332568 0.75 ANPEP (0.50) ANPEPLAP3
SCHEMBL23969659 0.72 ANPEP (0.55) ANPEPLAP3
SCHEMBL16526079 0.72 ANPEP (0.55) ANPEPLAP3
SCHEMBL24526101 0.72 ANPEP (0.55) ANPEPLAP3
SCHEMBL20234933 0.72 ANPEP (0.55) ANPEPLAP3
SCHEMBL15249536 0.71 ANPEP (0.60) ANPEPLAP3
SCHEMBL22103066 0.71 ANPEP (0.60) ANPEPLAP3
SCHEMBL21190520 0.71 ANPEP (0.60) ANPEPLAP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5736535-A 1-pyrimidinylacetamide compounds which are inhibitors of human leukocyte elastase ZENECA LIMITED (GB) 1998-04-07 US disclosed
EP-0636143-B1 ALPHA-AMINOBORONIC ACID PEPTIDES AND THEIR USE AS ELASTASE INHIBITORS ZENECA LTD (GB) 1997-09-24 EP disclosed
WO-1993021213-A1 ALPHA-AMINOBORONIC ACID PEPTIDES AND THEIR USE AS ELASTASE INHIBITORS ZENECA LIMITED (GB) 1993-10-28 WO disclosed
US-4537773-A α-Aminoboronic acid derivatives E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-08-27 US disclosed