Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9129576 | 0.96 | MEN1 (0.34) | MEN1HTTKMT2AL3MBTL1 | |
| SCHEMBL20974178 | 0.82 | MEN1 (0.34) | MEN1HTTKMT2AL3MBTL1 | |
| SCHEMBL1979048 | 0.80 | MEN1 (0.33) | MEN1HTTKMT2AL3MBTL1 | |
| SCHEMBL13731404 | 0.80 | MEN1 (0.33) | MEN1HTTKMT2AL3MBTL1 | |
| SCHEMBL1952760 | 0.80 | MEN1 (0.33) | MEN1HTTKMT2AL3MBTL1 | |
| SCHEMBL18625549 | 0.78 | TSHR (0.37) | MEN1HTTKMT2AL3MBTL1 | |
| SCHEMBL2788268 | 0.77 | ACACB (0.33) | MEN1HTTKMT2AL3MBTL1 | |
| SCHEMBL18340854 | 0.77 | ACACB (0.33) | MEN1HTTKMT2AL3MBTL1 | |
| SCHEMBL1980174 | 0.77 | MEN1 (0.32) | MEN1HTTKMT2AL3MBTL1 | |
| SCHEMBL1965298 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018866-A2 | 1,4-DIAMINO-2,3-DIHYDROXYBUTANES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1991-12-12 | — | — | WO | disclosed |