Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 4/20 | 0.33 |
| ▸ | CA1 | P00915 | 4/20 | 0.33 |
| ▸ | CA2 | P00918 | 4/20 | 0.33 |
| ▸ | CA9 | Q16790 | 4/20 | 0.33 |
| ▸ | CA7 | P43166 | 3/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL571478 | 0.89 | TSHR (0.50) | TSHRHCAR2CA12CA1CA2 | |
| SCHEMBL8636434 | 0.89 | TSHR (0.50) | TSHRHCAR2CA12CA1CA2 | |
| SCHEMBL1338978 | 0.89 | TSHR (0.50) | TSHRHCAR2CA12CA1CA2 | |
| SCHEMBL1336756 | 0.89 | TSHR (0.50) | TSHRHCAR2CA12CA1CA2 | |
| Ethylene Glycol SCHEMBL28051222 | 0.80 | TSHR (0.42) | TSHRHCAR2CA12CA1CA2 | |
| Cadaverine Tartrate SCHEMBL27575429 | 0.80 | TSHR (0.50) | TSHRHCAR2CA12CA1CA2 | |
| SCHEMBL5482220 | 0.80 | TSHR (0.50) | TSHRHCAR2CA12CA1CA2 | |
| SCHEMBL882439 | 0.79 | TSHR (0.46) | TSHRHCAR2CA12CA1CA2 | |
| SCHEMBL12951517 | 0.79 | TSHR (0.46) | TSHRHCAR2CA12CA1CA2 | |
| SCHEMBL2244398 | 0.77 | TSHR (0.43) | TSHRHCAR2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491149-A | VIRICIDES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-02-13 | — | — | US | disclosed |