Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.75 |
| ▸ | MAOB | P27338 | 2/20 | 0.75 |
| ▸ | MAPT | P10636 | 7/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.64 |
| ▸ | HPGD | P15428 | 8/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.64 |
| ▸ | TSHR | P16473 | 5/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | APEX1 | P27695 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | AR | P10275 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5618032 | 0.83 | MAOB (0.77) | MAOBAR | |
| SCHEMBL5618481 | 0.81 | MAOB (0.77) | MAOBALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL5617810 | 0.80 | NPC1 (0.76) | TDP1MAOBALDH1A1KDM4EHPGD | |
| SCHEMBL7427852 | 0.79 | MAOB (0.63) | MAOBALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL7440445 | 0.79 | MAOB (0.63) | MAOBAR | |
| SCHEMBL7303229 | 0.78 | TDP1 (0.60) | TDP1MAOBMAPTALDH1A1KDM4E | |
| SCHEMBL4708735 | 0.78 | KDM4E (0.95) | MAPTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL10020983 | 0.78 | TDP1 (0.96) | TDP1MAOBMAPTALDH1A1KDM4E | |
| SCHEMBL5617809 | 0.78 | MAOB (0.68) | MAOBRAB9AAR | |
| SCHEMBL13556494 | 0.77 | TDP1 (0.79) | TDP1MAOBMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0363793-B1 | ARYL ALKOXY COUMARINS, PROCESS FOR THEIR PRODUCTION AND THERAPEUTIC AGENTS CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1993-04-21 | — | — | EP | disclosed |
| US-5100914-A | Monoamine Oxidase Inhibitors, Central Nervous System Disorders | BASF AKTIENGESELLSCHAFT (DE) | 1992-03-31 | — | — | US | disclosed |
| EP-0363793-A1 | Aryl alkoxy coumarins, process for their production and therapeutic agents containing them | BASF Aktiengesellschaft (DE) | 1990-04-18 | — | — | EP | disclosed |