Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.36 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL335137 | 0.89 | TDP1 (0.46) | MEN1KMT2AGAAHCRTR2DRD2 | |
| SCHEMBL21930398 | 0.86 | MEN1 (0.41) | MEN1KMT2AGAAHCRTR2DRD2 | |
| SCHEMBL7609309 | 0.86 | MEN1 (0.41) | MEN1KMT2AGAAHCRTR2DRD2 | |
| SCHEMBL6803134 | 0.84 | EPHX1 (0.42) | MEN1KMT2AGAAHCRTR2DRD2 | |
| SCHEMBL1970278 | 0.82 | HCRTR2 (0.44) | MEN1KMT2AGAAHCRTR2DRD2 | |
| SCHEMBL3490738 | 0.78 | USP2 (0.42) | MEN1KMT2AHCRTR2EPHX1ALDH1A1 | |
| SCHEMBL23200870 | 0.78 | MEN1 (0.41) | MEN1KMT2AGAAHCRTR2TDP1 | |
| SCHEMBL24868403 | 0.77 | KMT2A (0.40) | MEN1KMT2AGAAHCRTR2TDP1 | |
| SCHEMBL12231002 | 0.76 | TDP1 (0.46) | MEN1KMT2AGAAHCRTR2DRD2 | |
| SCHEMBL16076549 | 0.76 | TDP1 (0.46) | MEN1KMT2AGAAHCRTR2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4873253-A | Phenylalanine derivative and proteinase inhibitor | Okamoto, Shosuke (JP) | 1989-10-10 | — | — | US | disclosed |