Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 19/20 | 0.55 |
| ▸ | PRSS2 | P07478 | 6/20 | 0.55 |
| ▸ | CTRC | Q99895 | 6/20 | 0.54 |
| ▸ | F10 | P00742 | 4/20 | 0.54 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7608163 | 0.91 | EPHX2 (0.51) | F2PRSS2F10KCNA5 | |
| SCHEMBL6553561 | 0.85 | CD274 (0.49) | KCNA5 | |
| SCHEMBL6553001 | 0.85 | F2 (0.76) | F2PRSS2CTRCF10 | |
| Acetic Acid SCHEMBL7451815 | 0.84 | F2 (0.68) | F2PRSS2CTRCF10 | |
| SCHEMBL7442140 | 0.82 | F2 (0.48) | F2PRSS2CTRCF10 | |
| SCHEMBL7446659 | 0.82 | F2 (0.59) | F2PRSS2CTRCF10 | |
| Acetic Acid SCHEMBL7603777 | 0.80 | F2 (0.58) | F2PRSS2CTRCF10 | |
| SCHEMBL7443994 | 0.80 | F2 (0.76) | F2PRSS2CTRCF10 | |
| SCHEMBL6554531 | 0.78 | F2 (0.75) | F2PRSS2CTRCF10 | |
| SCHEMBL7601940 | 0.78 | F2 (0.75) | F2PRSS2CTRCF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0859607-B1 | GUANIDINO PROTEASE INHIBITORS | DIMENSIONAL PHARM INC (US) | 2002-12-18 | — | — | EP | disclosed |
| EP-0859607-A4 | GUANIDINO PROTEASE INHIBITORS | DIMENSIONAL PHARM INC (US) | 1999-05-06 | — | — | EP | disclosed |
| EP-0859607-A1 | GUANIDINO PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1998-08-26 | — | — | EP | disclosed |
| WO-1997011693-A1 | GUANIDINO PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1997-04-03 | — | — | WO | disclosed |