Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442358 | 1.00 | BCHE (0.42) | BCHEACHEPOLBGAAMAPK1 | |
| SCHEMBL9455988 | 1.00 | BCHE (0.42) | BCHEACHEPOLBGAAMAPK1 | |
| SCHEMBL7434635 | 1.00 | BCHE (0.42) | BCHEACHEPOLBGAAMAPK1 | |
| SCHEMBL6373342 | 0.96 | BCHE (0.43) | BCHEACHEPOLBGAAMAPK1 | |
| SCHEMBL9456017 | 0.92 | BCHE (0.38) | BCHEACHEPOLBGAAMAPK1 | |
| SCHEMBL7434499 | 0.92 | BCHE (0.38) | BCHEACHEPOLBGAAMAPK1 | |
| SCHEMBL9456009 | 0.92 | BCHE (0.38) | BCHEACHEPOLBGAAMAPK1 | |
| SCHEMBL6373215 | 0.92 | BCHE (0.38) | BCHEACHEPOLBGAAMAPK1 | |
| SCHEMBL4870268 | 0.91 | POLB (0.39) | BCHEACHEPOLBGAAMAPK1 | |
| SCHEMBL4873069 | 0.91 | POLB (0.39) | BCHEACHEPOLBGAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520372-B1 | Inositol phosphate analogues as calcium-antagonistic substances | HOECHST AG (DE) | 1996-12-04 | — | — | EP | disclosed |
| US-5395828-A | Cardiovascular | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-03-07 | — | — | US | disclosed |
| EP-0520372-A1 | Inositol phosphate analogues as calcium-antagonistic substances | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-12-30 | — | — | EP | disclosed |