Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 17/20 | 0.70 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7768043 | 0.94 | F2 (0.71) | F2ESR1ESR2HRH3 | |
| SCHEMBL7443028 | 0.88 | F2 (0.79) | F2ESR1ESR2 | |
| SCHEMBL6595508 | 0.87 | F2 (0.91) | F2ESR1ESR2 | |
| SCHEMBL7443800 | 0.86 | F2 (0.61) | F2ESR1ESR2HRH3 | |
| SCHEMBL7440461 | 0.84 | F2 (0.61) | F2ESR1ESR2 | |
| SCHEMBL6595431 | 0.83 | F2 (0.81) | F2ESR1ESR2 | |
| SCHEMBL6594826 | 0.82 | F2 (1.00) | F2ESR1ESR2 | |
| SCHEMBL6597428 | 0.81 | F2 (1.00) | F2ESR1ESR2 | |
| SCHEMBL7773838 | 0.80 | F2 (0.60) | F2ESR1ESR2HRH3 | |
| SCHEMBL7771695 | 0.79 | ESR1 (0.67) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863755-A4 | ANTITHROMBOTIC DIAMINES | LILLY CO ELI (US) | 1999-01-20 | — | — | EP | disclosed |
| EP-0863755-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997025033-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |