Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 7/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7830026 | 0.84 | F2 (0.51) | F2CD274ESR1FFAR1 | |
| SCHEMBL7809457 | 0.83 | F2 (0.41) | F2CD274LTA4HFFAR1 | |
| SCHEMBL7504385 | 0.83 | F2 (0.53) | F2LTA4HHRH3ESR1 | |
| SCHEMBL7772445 | 0.82 | F2 (0.65) | F2ESR1 | |
| SCHEMBL7772447 | 0.82 | F2 (0.65) | F2ESR1 | |
| SCHEMBL7507451 | 0.81 | POLB (0.54) | — | |
| SCHEMBL7452204 | 0.77 | HRH3 (0.55) | F2LTA4HHRH3 | |
| SCHEMBL7818611 | 0.76 | F2 (0.48) | F2HRH3ESR1 | |
| SCHEMBL7818365 | 0.76 | S1PR1 (0.45) | F2CD274HRH3 | |
| SCHEMBL7452240 | 0.75 | F2 (0.56) | F2LTA4HHRH3ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863755-A4 | ANTITHROMBOTIC DIAMINES | LILLY CO ELI (US) | 1999-01-20 | — | — | EP | disclosed |
| EP-0863755-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997025033-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |