Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.51 |
| ▸ | BCL2 | P10415 | 1/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2421148 | 0.92 | MAPK9 (0.57) | MAPK9MAPK10BCL2BCL2L1MEN1 | |
| SCHEMBL2423073 | 0.92 | MAPK9 (0.55) | MAPK9MAPK10BCL2BCL2L1MEN1 | |
| SCHEMBL2423054 | 0.88 | MAPK9 (0.59) | MAPK9MAPK10BCL2BCL2L1MEN1 | |
| SCHEMBL2428129 | 0.84 | MAPK9 (0.56) | MAPK9MAPK10BCL2BCL2L1MEN1 | |
| SCHEMBL2422491 | 0.83 | MAPT (0.58) | MAPK9MAPK10BCL2BCL2L1MEN1 | |
| SCHEMBL2424858 | 0.83 | MAPK9 (0.61) | MAPK9MAPK10BCL2BCL2L1MEN1 | |
| SCHEMBL2421411 | 0.82 | MAPK9 (0.53) | MAPK9MAPK10BCL2BCL2L1MEN1 | |
| SCHEMBL2421831 | 0.82 | MAPK9 (0.55) | MAPK9MAPK10BCL2BCL2L1MEN1 | |
| SCHEMBL7894679 | 0.80 | MAPK9 (0.54) | MAPK9MAPK10BCL2BCL2L1MEN1 | |
| SCHEMBL2422063 | 0.80 | MAPK9 (0.52) | MAPK9MAPK10BCL2BCL2L1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218374-A1 | PHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES | Applied Research Systems ARS Holding N.V. (AN) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001023378-A1 | PHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-04-05 | — | — | WO | disclosed |