SCHEMBL7440642

SCHEMBL7440642

CC(C)(C)OC(=O)N1CCCC(NC=O)C1

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.51
USP30 Q70CQ3 4/20 0.50
MEN1 O00255 1/20 0.49
ALDH1A1 P00352 1/20 0.49
MAPT P10636 1/20 0.49
KMT2A Q03164 1/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
HPGD P15428 1/20 0.47
HDAC4 P56524 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
FPR2 P25090 2/20 0.43
PARP1 P09874 1/20 0.43
FPR3 P25089 1/20 0.43
GLS O94925 2/20 0.43
BRD4 O60885 1/20 0.41
CYP2C9 P11712 1/20 0.40
HSD11B1 P28845 1/20 0.40
PREP P48147 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27760995 1.00 EPHX1 (0.51) EPHX1USP30MEN1ALDH1A1MAPT
SCHEMBL13696781 0.91 EPHX1 (0.54) EPHX1USP30MEN1ALDH1A1MAPT
SCHEMBL9151419 0.91 EPHX1 (0.54) EPHX1USP30MEN1ALDH1A1MAPT
SCHEMBL29012258 0.85 EPHX1 (0.54) EPHX1USP30MEN1ALDH1A1MAPT
SCHEMBL29012259 0.85 EPHX1 (0.54) EPHX1USP30MEN1ALDH1A1MAPT
SCHEMBL28779715 0.85 EPHX1 (0.54) EPHX1USP30MEN1ALDH1A1MAPT
SCHEMBL4268788 0.85 EPHX1 (0.54) EPHX1USP30MEN1ALDH1A1MAPT
SCHEMBL28779698 0.85 EPHX1 (0.57) EPHX1USP30MEN1ALDH1A1MAPT
SCHEMBL5666472 0.85 EPHX1 (0.57) EPHX1USP30MEN1ALDH1A1MAPT
SCHEMBL17699916 0.85 EPHX1 (0.54) EPHX1USP30MEN1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101565397-B N-Boc-3-aminopiperidine and synthesizing method of optical isomer thereof ZHEJIANG MED XINCHANG PHARM 2011-08-10 CN claimed
CN-101565397-A N-Boc-3-aminopiperidine and synthesizing method of optical isomer thereof ZHEJIANG MEDICINE CO LTD (CN) 2009-10-28 CN claimed
CN-118755684-A Catalytic enzyme for producing chiral aromatic amine, N-heterocyclic amine and derivatives thereof with high optical purity, and preparation method and application thereof 杭州微远生物科技有限公司 2024-10-11 CN disclosed
CN-110724675-B Transaminase catalyst and method for synthesizing (R) -1-tert-butoxycarbonyl-3-aminopiperidine by enzyme method 宁波酶赛生物工程有限公司 2021-02-02 CN disclosed
CN-110724675-A Transaminase catalyst and method for synthesizing (R) -1-tert-butoxycarbonyl-3-aminopiperidine by enzyme method 宁波酶赛生物工程有限公司 2020-01-24 CN disclosed
CN-101565397-B N-Boc-3-aminopiperidine and synthesizing method of optical isomer thereof ZHEJIANG MED XINCHANG PHARM 2011-08-10 CN disclosed
CN-101565397-B N-Boc-3-aminopiperidine and synthesizing method of optical isomer thereof ZHEJIANG MED XINCHANG PHARM 2011-08-10 CN disclosed
CN-101565397-A N-Boc-3-aminopiperidine and synthesizing method of optical isomer thereof ZHEJIANG MEDICINE CO LTD (CN) 2009-10-28 CN disclosed
CN-101565397-A N-Boc-3-aminopiperidine and synthesizing method of optical isomer thereof ZHEJIANG MEDICINE CO LTD (CN) 2009-10-28 CN disclosed
US-5571832-A Nitrogen-containing cyclohetero alkylamino aryl derivatives for CNS disorders THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1996-11-05 US disclosed