Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 14/20 | 0.59 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.56 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.56 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.56 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7445650 | 0.85 | DRD1 (0.74) | DRD1 | |
| SCHEMBL7445624 | 0.85 | DRD1 (0.74) | DRD1 | |
| SCHEMBL7446537 | 0.82 | DRD1 (0.59) | DRD1ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL7441116 | 0.82 | DRD1 (0.59) | DRD1ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL7450696 | 0.81 | DRD1 (0.74) | DRD1ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL10381345 | 0.81 | DRD1 (0.74) | DRD1ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL10380807 | 0.81 | DRD1 (0.74) | DRD1ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL7450347 | 0.81 | DRD1 (0.72) | DRD1ADRA2AADRA2BADRA2CADRA1D | |
| Hydrochloric Acid SCHEMBL8903330 | 0.81 | DRD1 (0.72) | DRD1ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL7452173 | 0.81 | DRD1 (0.73) | DRD1ADRA2AADRA2BADRA2CADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5621133-A | PREPARING A 1-(3,4-DIALKOXYPHENYL),3-HYDROXYALKANE(C6-C12) BY EPOXIDIZING A HALO DERIVATIVE WITH A BASE FOLLOWED BY DECYCLICIZING WITH AN ORGANOMETALLIC COMPOUND IN A SOLVENT; NAPHTHYLENES, ISOCHROMENES AND ISOTHIOCHROMENES | DENINNO MICHAEL P (US) | 1997-04-15 | — | — | US | disclosed |
| US-5591884-A | PROTECTED HYDROXYALKYLCATECHOL INTERMEDIATES | ABBOTT LABORATORIES (US) | 1997-01-07 | — | — | US | disclosed |
| WO-1996038435-A1 | DOPAMINE AGONISTS | ABBOTT LABORATORIES (US) | 1996-12-05 | — | — | WO | disclosed |