Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 1/20 | 0.69 |
| ▸ | MAGI3 | Q5TCQ9 | 1/20 | 0.66 |
| ▸ | CASP1 | P29466 | 2/20 | 0.54 |
| ▸ | CASP3 | P42574 | 2/20 | 0.54 |
| ▸ | CASP7 | P55210 | 2/20 | 0.54 |
| ▸ | CASP4 | P49662 | 1/20 | 0.54 |
| ▸ | CASP5 | P51878 | 1/20 | 0.54 |
| ▸ | CASP9 | P55211 | 1/20 | 0.54 |
| ▸ | CASP6 | P55212 | 1/20 | 0.54 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.54 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.54 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.53 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ACE | P12821 | 2/20 | 0.50 |
| ▸ | ECE1 | P42892 | 2/20 | 0.49 |
| ▸ | CCKAR | P32238 | 2/20 | 0.49 |
| ▸ | CCKBR | P32239 | 2/20 | 0.49 |
| ▸ | MMP2 | P08253 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442648 | 1.00 | EDNRA (0.69) | EDNRAMAGI3CASP1CASP3CASP7 | |
| SCHEMBL7392689 | 0.95 | MAGI3 (0.72) | EDNRAMAGI3CASP1CASP3CASP7 | |
| SCHEMBL7392686 | 0.95 | MAGI3 (0.72) | EDNRAMAGI3CASP1CASP3CASP7 | |
| SCHEMBL7401384 | 0.94 | MAGI3 (0.68) | EDNRAMAGI3CASP1CASP3CASP7 | |
| SCHEMBL7401386 | 0.94 | MAGI3 (0.68) | EDNRAMAGI3CASP1CASP3CASP7 | |
| SCHEMBL7401403 | 0.93 | EDNRA (0.62) | EDNRAMAGI3CASP1CASP3CASP7 | |
| SCHEMBL7401397 | 0.93 | EDNRA (0.62) | EDNRAMAGI3CASP1CASP3CASP7 | |
| SCHEMBL7495581 | 0.93 | MAGI3 (0.65) | EDNRAMAGI3CASP1CASP3CASP7 | |
| SCHEMBL7495576 | 0.93 | MAGI3 (0.65) | EDNRAMAGI3CASP1CASP3CASP7 | |
| SCHEMBL7400884 | 0.93 | EDNRA (0.76) | EDNRAMAGI3CASP1CASP3CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5504070-A | ADMINISTERING OLIGOPEPTIDES, PHOSPHONATES AND MODIFIED AMINO ACIDS AS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1996-04-02 | — | — | US | claimed |
| US-5504070-A | ADMINISTERING OLIGOPEPTIDES, PHOSPHONATES AND MODIFIED AMINO ACIDS AS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1996-04-02 | — | — | US | disclosed |
| WO-1993011154-A1 | INHIBITORS OF THE CONVERSION OF BIG ENDOTHELIN TO ENDOTHELIN | BERLEX LABORATORIES, INC. (US) | 1993-06-10 | — | — | WO | disclosed |