Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.35 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1432658 | 0.83 | SMPD2 (0.41) | BACE1CTSSCTSKKDM4EALDH1A1 | |
| SCHEMBL7229620 | 0.83 | SMPD2 (0.41) | BACE1CTSSCTSKKDM4EALDH1A1 | |
| SCHEMBL1326634 | 0.83 | SMPD2 (0.41) | BACE1CTSSCTSKKDM4EALDH1A1 | |
| SCHEMBL27597531 | 0.81 | MEN1 (0.40) | BACE1CTSSCTSKKDM4EALDH1A1 | |
| SCHEMBL6139113 | 0.81 | MEN1 (0.40) | BACE1CTSSCTSKKDM4EALDH1A1 | |
| SCHEMBL3288030 | 0.78 | SMN1; SMN2 (0.43) | ALDH1A1TDP1HSD17B10L3MBTL1KMT2A | |
| SCHEMBL1134230 | 0.78 | SMN1; SMN2 (0.43) | ALDH1A1TDP1HSD17B10L3MBTL1KMT2A | |
| SCHEMBL6237773 | 0.78 | BACE1 (0.45) | BACE1CTSSALDH1A1KMT2AHPGD | |
| SCHEMBL8628583 | 0.77 | BACE1 (0.36) | BACE1CTSSCTSKKDM4EALDH1A1 | |
| SCHEMBL6832915 | 0.77 | SMN1; SMN2 (0.40) | CTSSCTSKALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616605-A | Peptide derivatives of collagenase inhibitor | RESEARCH CORPORATION TECH., INC. (US) | 1997-04-01 | — | — | US | disclosed |
| US-5387610-A | Treating rheumatoid arthritis, corneal ulceration | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1995-02-07 | — | — | US | disclosed |
| WO-1992022523-A2 | PEPTIDE DERIVATIVES OF COLLAGENASE INHIBITOR | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1992-12-23 | — | — | WO | disclosed |