Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 14/20 | 0.48 |
| ▸ | NPY1R | P25929 | 10/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.48 |
| ▸ | NPY2R | P49146 | 5/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.35 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1227661 | 0.89 | NPY4R (0.53) | NPY4RNPY1RNPY5RNPY2RDPP7 | |
| SCHEMBL7448599 | 0.89 | DPP7 (0.49) | NPY4RNPY1RNPY5RNPY2RDPP7 | |
| SCHEMBL16316768 | 0.85 | NPY4R (0.53) | NPY4RNPY1RNPY5RNPY2RDPP7 | |
| SCHEMBL29447204 | 0.84 | NPY4R (0.50) | NPY4RNPY1RNPY5RNPY2RDPP7 | |
| SCHEMBL6366210 | 0.83 | NPY4R (0.59) | NPY4RNPY1RNPY5RNPY2RDPP7 | |
| SCHEMBL6362150 | 0.83 | NPY4R (0.59) | NPY4RNPY1RNPY5RNPY2RDPP7 | |
| SCHEMBL29947131 | 0.83 | NPY4R (0.59) | NPY4RNPY1RNPY5RNPY2RDPP7 | |
| SCHEMBL6366206 | 0.83 | NPY4R (0.59) | NPY4RNPY1RNPY5RNPY2RDPP7 | |
| SCHEMBL19267519 | 0.83 | NPY4R (0.59) | NPY4RNPY1RNPY5RNPY2RDPP7 | |
| SCHEMBL29947199 | 0.83 | NPY4R (0.59) | NPY4RNPY1RNPY5RNPY2RDPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6063819-A | PROTECTING NEURONS FROM DAMAGE BY ADMINISTERING TO HUMANS POLYGUADINO COMPOUNDS | CYPROS PHARMACEUTICAL CORP. (US) | 2000-05-16 | — | — | US | disclosed |
| WO-1998036743-A1 | NEUROPROTECTIVE POLY-GUANIDINO COMPOUNDS WHICH BLOCK PRESYNAPTIC N AND P/Q CALCIUM CHANNELS | CYPROS PHARMACEUTICAL CORPORATION (US) | 1998-08-27 | — | — | WO | disclosed |