Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.47 |
| ▸ | DPP4 | P27487 | 10/20 | 0.46 |
| ▸ | FAP | Q12884 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 4/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | PREP | P48147 | 1/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7443905 | 0.89 | F2 (0.49) | F2DPP4FAPALDH1A1ELANE | |
| Trifluoroacetic Acid SCHEMBL7452129 | 0.81 | F2 (0.49) | F2DPP4FAPALDH1A1ELANE | |
| Trifluoroacetic Acid SCHEMBL7449971 | 0.76 | F2 (0.48) | F2DPP4FAPALDH1A1ELANE | |
| SCHEMBL21429847 | 0.76 | F2 (0.59) | F2ALDH1A1PKMF10PRSS1 | |
| Trifluoroacetic Acid SCHEMBL7447612 | 0.74 | F2 (0.49) | F2DPP4FAPALDH1A1ELANE | |
| SCHEMBL16277243 | 0.71 | F2 (0.55) | F2ALDH1A1PKMF10PRSS1 | |
| SCHEMBL21430304 | 0.70 | F2 (0.56) | F2ALDH1A1PKMCYP3A4CYP2C9 | |
| SCHEMBL26616542 | 0.69 | ACE (0.55) | FAPPREP | |
| SCHEMBL26616535 | 0.69 | ACE (0.55) | FAPPREP | |
| SCHEMBL5967094 | 0.69 | ACE (0.52) | FAPALDH1A1PREPCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001027096-A9 | AMINOMETHYL-(HETERO)ARYL DERIVATIVES AND THEIR USE AS TRYPTASE INHIBITORS | PROTHERICS MOLECULAR DESIGN LT (GB) | 2001-07-12 | — | — | WO | disclosed |
| WO-2001027096-A1 | AMINOMETHYL-(HETERO)ARYL DERIVATIVES AND THEIR USE AS TRYPTASE INHIBITORS | TULARIK LIMITED (GB) | 2001-04-19 | — | — | WO | disclosed |