SCHEMBL74440

SCHEMBL74440

OC12CCN(CC1)C2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3317045 0.69
SCHEMBL22784457 0.60
Hydrochloric Acid SCHEMBL21408509 0.58
SCHEMBL22511391 0.56
SCHEMBL12956299 0.55 ATM (0.33)
SCHEMBL6120741 0.55
SCHEMBL227443 0.52
SCHEMBL14642206 0.52
SCHEMBL6015697 0.52
SCHEMBL1434434 0.50

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630562-B2 Piperidylurea compounds and methods of use thereof ARCUS BIOSCIENCES, INC. (US) 2026-05-19 US disclosed
US-20260042777-A1 PIPERIDYLUREA COMPOUNDS AND METHODS OF USE THEREOF ARCUS BIOSCIENCES, INC. (US) 2026-02-12 US disclosed
US-20250275959-A1 COMPOUNDS AND METHODS OF THEIR USE LEXICON PHARMACEUTICALS, INC. 2025-09-04 US disclosed
US-10588895-B2 Quinuclidine derivatives and medicinal compositions containing the same ALMIRALL, S.A. (ES) 2020-03-17 US disclosed
US-20190183867-A1 NOVEL QUINUCLIDINE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME ALMIRALL SA (ES) 2019-06-20 US disclosed
US-10034867-B2 Quinuclidine derivatives and medicinal compositions containing the same ALMIRALL, S.A. (ES) 2018-07-31 US disclosed
US-20170319557-A1 NOVEL QUINUCLIDINE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME ALMIRALL PRODESFARMA, S.A. (ES) 2017-11-09 US disclosed
US-9687478-B2 Quinuclidine derivatives and medicinal compositions containing the same ALMIRALL, S.A. (ES) 2017-06-27 US disclosed
US-RE46417-E1 Quinuclidine derivatives and their use as muscarinic M3 receptor ligands ALMIRALL, S.A. (ES) 2017-05-30 US disclosed
US-20160296503-A1 NOVEL QUINUCLIDINE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME ALMIRALL PRODESFARMA, S.A. (ES) 2016-10-13 US disclosed
WO-2002051841-A1 QUINUCLIDINE CARBAMATE DERIVATIVES AND THEIR USE AS M3 ANTAGONISTS ALMIRALL PRODESFARMA AG (CH) 2002-07-04 WO disclosed
EP-0287116-B1 Thiadiazolylacetamide cephem derivatives EISAI CO LTD (JP) 1995-03-15 EP disclosed
EP-0625981-A1 AZABICYCLO COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS SMITHKLINE BEECHAM PLC (GB) 1994-11-30 EP disclosed
WO-1993015080-A1 AZABICYCLO COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS SMITHKLINE BEECHAM PLC (GB) 1993-08-05 WO disclosed
US-5010188-A Cephem derivatives EISAI CO., LTD. (JP) 1991-04-23 US disclosed
US-5008260-A Bactericides EISAI CO., LTD. (JP) 1991-04-16 US disclosed
EP-0188255-B1 CEPHEM DERIVATIVES Eisai Co., Ltd. (JP) 1991-04-03 EP disclosed
US-4929612-A ANTIBIOTICS, BACTERICIDES EISAI CO., LTD. (JP) 1990-05-29 US disclosed
US-4748171-A Cephem compounds having at the 3-position a (1,4-methylene-1-piperidinio)methyl group or a (1-quinuclidinio)methyl group EISAI CO., LTD. (JP) 1988-05-31 US disclosed
EP-0188255-A2 Cephem derivatives Eisai Co., Ltd. (JP) 1986-07-23 EP disclosed