Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9297595 | 1.00 | USP30 (0.37) | USP30ALOX5SCN8A | |
| SCHEMBL1116532 | 0.88 | USP30 (0.37) | USP30SCN8A | |
| SCHEMBL7297273 | 0.88 | USP30 (0.37) | USP30SCN8A | |
| SCHEMBL27454880 | 0.86 | USP30 (0.36) | USP30SCN8A | |
| SCHEMBL6210430 | 0.86 | USP30 (0.36) | USP30SCN8A | |
| SCHEMBL7277631 | 0.82 | USP30 (0.37) | USP30SCN8A | |
| SCHEMBL7277620 | 0.82 | USP30 (0.37) | USP30SCN8A | |
| SCHEMBL7340517 | 0.82 | USP30 (0.37) | USP30SCN8A | |
| SCHEMBL9556824 | 0.80 | — | — | |
| SCHEMBL9556659 | 0.78 | XIAP (0.31) | USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5258362-A | Enzyme inhibitors, amides with oxetane ring | ABBOTT LABORATORIES (US) | 1993-11-02 | — | — | US | disclosed |
| EP-0416393-A1 | Peptidyl difluorodiol renin inhibitors | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | disclosed |