Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Anisole SCHEMBL7562607 | 0.88 | CA4 (0.61) | CA4CES2CES1CA1CA2 | |
| Anisole SCHEMBL28145757 | 0.88 | CA4 (0.61) | CA4CES2CES1CA1CA2 | |
| Anisole SCHEMBL28177334 | 0.88 | CA4 (0.61) | CA4CES2CES1CA1CA2 | |
| Anisole SCHEMBL250580 | 0.88 | CA4 (0.61) | CA4CES2CES1CA1CA2 | |
| Anisole SCHEMBL2335694 | 0.84 | CA4 (0.52) | CA4CES2CES1PPARGPPARA | |
| Anisole SCHEMBL1919865 | 0.84 | CA4 (0.67) | CA4CES2CES1CA1CA2 | |
| Anisole SCHEMBL28945470 | 0.83 | CA4 (0.50) | CA4CES2CES1PPARGPPARA | |
| Anisole SCHEMBL6283700 | 0.82 | CA4 (0.64) | CA4CES2CES1CA1CA2 | |
| Anisole SCHEMBL7204405 | 0.79 | CA4 (0.50) | CA4CES2CES1CA1CA2 | |
| Anisole SCHEMBL4623600 | 0.79 | CA4 (0.45) | CA4CES2CES1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0095295-B1 | CYCLIC PEPTIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1987-01-14 | — | — | EP | disclosed |
| US-4537717-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1985-08-27 | — | — | US | disclosed |