SCHEMBL7444446

SCHEMBL7444446

NC(Cc1cncs1)CC(O)C(N)Cc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CSNK1E P49674 1/20 0.44
EPHX1 P07099 1/20 0.41
SLC6A3 Q01959 1/20 0.38
ANPEP P15144 1/20 0.37
GPR142 Q7Z601 7/20 0.37
SLC15A1 P46059 1/20 0.36
CYP3A4 P08684 3/20 0.36
CTSC P53634 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
F2 P00734 1/20 0.35
TRPA1 O75762 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7179401 1.00 CSNK1E (0.44) CSNK1EEPHX1SLC6A3ANPEPGPR142
SCHEMBL7195304 0.81 EPHX1 (0.61) CSNK1EEPHX1SLC6A3ANPEPSLC15A1
SCHEMBL30025452 0.81 EPHX1 (0.61) CSNK1EEPHX1SLC6A3ANPEPSLC15A1
SCHEMBL7797835 0.81 EPHX1 (0.61) CSNK1EEPHX1SLC6A3ANPEPSLC15A1
SCHEMBL2436429 0.81 EPHX1 (0.61) CSNK1EEPHX1SLC6A3ANPEPSLC15A1
SCHEMBL7308044 0.81 EPHX1 (0.61) CSNK1EEPHX1SLC6A3ANPEPSLC15A1
Hydrochloric Acid SCHEMBL8972242 0.80 EPHX1 (0.59) CSNK1EEPHX1SLC6A3ANPEPSLC15A1
Hydrochloric Acid SCHEMBL7095630 0.80 EPHX1 (0.59) CSNK1EEPHX1SLC6A3ANPEPSLC15A1
Hydrochloric Acid SCHEMBL7499120 0.80 EPHX1 (0.59) CSNK1EEPHX1SLC6A3ANPEPSLC15A1
Hydrochloric Acid SCHEMBL8947219 0.80 EPHX1 (0.59) CSNK1EEPHX1SLC6A3ANPEPSLC15A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1994014436-A1 RETROVIRAL PROTEASE INHIBITING COMPOUNDS ABBOTT LABORATORIES (US) 1994-07-07 WO disclosed