Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 16/20 | 0.84 |
| ▸ | EDNRA | P25101 | 16/20 | 0.84 |
| ▸ | TACR1 | P25103 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8860873 | 0.92 | EDNRB (0.83) | EDNRBEDNRA | |
| SCHEMBL7450437 | 0.91 | EDNRB (1.00) | EDNRBEDNRA | |
| SCHEMBL7446167 | 0.90 | EDNRB (0.83) | EDNRBEDNRATACR1 | |
| SCHEMBL7446854 | 0.89 | EDNRB (0.70) | EDNRBEDNRATACR1 | |
| SCHEMBL7437360 | 0.89 | EDNRB (0.79) | EDNRBEDNRATACR1 | |
| SCHEMBL18222569 | 0.88 | EDNRB (0.82) | EDNRBEDNRATACR1 | |
| SCHEMBL7443267 | 0.88 | EDNRB (0.82) | EDNRBEDNRATACR1 | |
| SCHEMBL7444422 | 0.88 | EDNRB (0.82) | EDNRBEDNRATACR1 | |
| SCHEMBL29551459 | 0.88 | EDNRB (0.82) | EDNRBEDNRATACR1 | |
| SCHEMBL7431474 | 0.88 | EDNRB (0.75) | EDNRBEDNRATACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0753004-A1 | ANTAGONISTS OF ENDOTHELIN RECEPTORS | Japat Ltd (CH) | 1997-01-15 | — | — | EP | claimed |
| WO-1995026360-A1 | ANTAGONISTS OF ENDOTHELIN RECEPTORS | JAPAT LTD. (CH) | 1995-10-05 | — | — | WO | claimed |