Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.65 |
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.58 |
| ▸ | GRB2 | P62993 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.53 |
| ▸ | ALPI | P09923 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | XIAP | P98170 | 1/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.52 |
| ▸ | TPH1 | P17752 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5302819 | 0.88 | PTPN1 (0.50) | PTPN1SLC7A5GRB2PTGS1ALPI | |
| SCHEMBL15294492 | 0.84 | SLC7A5 (0.57) | PTPN1SLC7A5GRB2PTGS1ALPI | |
| SCHEMBL2930111 | 0.83 | SLC7A5 (0.51) | PTPN1SLC7A5GRB2PTGS1ALPI | |
| SCHEMBL451772 | 0.82 | SLC7A5 (0.62) | PTPN1SLC7A5GRB2PTGS1ALPI | |
| SCHEMBL23408849 | 0.82 | SLC7A5 (0.51) | PTPN1SLC7A5GRB2PTGS1ALPI | |
| SCHEMBL3952354 | 0.82 | PTPN1 (0.43) | PTPN1SLC7A5GRB2 | |
| SCHEMBL1802026 | 0.81 | PTPN1 (0.78) | PTPN1SLC7A5GRB2PTGS1ALPI | |
| SCHEMBL1802025 | 0.81 | PTPN1 (0.78) | PTPN1SLC7A5GRB2PTGS1ALPI | |
| SCHEMBL18256435 | 0.81 | PTPN1 (0.78) | PTPN1SLC7A5GRB2PTGS1ALPI | |
| SCHEMBL22645606 | 0.81 | SLC7A5 (0.61) | PTPN1SLC7A5GRB2PTGS1ALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0577775-A4 | ANTI-THROMBOTIC PEPTIDES AND PSEUDOPEPTIDES. | RHONE POULENC RORER INT (US) | 1995-01-11 | — | — | EP | disclosed |
| EP-0577775-A1 | ANTI-THROMBOTIC PEPTIDES AND PSEUDOPEPTIDES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1994-01-12 | — | — | EP | disclosed |
| WO-1992017196-A1 | ANTI-THROMBOTIC PEPTIDES AND PSEUDOPEPTIDES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-10-15 | — | — | WO | disclosed |