Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 19/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | THPO | P40225 | 1/20 | 0.56 |
| ▸ | MTOR | P42345 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7439885 | 1.00 | DRD1 (1.00) | DRD1KDM4ETP53CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL7320564 | 0.99 | DRD1 (0.97) | DRD1KDM4ETP53CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL8829240 | 0.99 | DRD1 (0.97) | DRD1KDM4ETP53CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL9670199 | 0.99 | DRD1 (0.97) | DRD1KDM4ETP53CYP3A4CYP2D6 | |
| SCHEMBL22952966 | 0.88 | DRD1 (0.79) | DRD1KDM4ETP53CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL7499546 | 0.85 | DRD1 (0.74) | DRD1KDM4ETP53CYP3A4CYP2D6 | |
| SCHEMBL7445741 | 0.84 | DRD1 (0.72) | DRD1KDM4ETP53CYP3A4CYP2D6 | |
| SCHEMBL7553387 | 0.84 | DRD1 (0.72) | DRD1KDM4ETP53CYP3A4CYP2D6 | |
| SCHEMBL7445455 | 0.84 | DRD1 (0.72) | DRD1KDM4ETP53CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL9039972 | 0.83 | DRD1 (0.70) | DRD1KDM4ETP53CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0474767-B1 | DOPAMINE AGONISTS | ABBOTT LAB (US) | 1996-02-21 | — | — | EP | claimed |
| EP-0474767-A4 | DOPAMINE AGONISTS | — | 1992-07-08 | — | — | EP | claimed |
| EP-0474767-A1 | DOPAMINE AGONISTS. | ABBOTT LAB (US) | 1992-03-18 | — | — | EP | claimed |
| WO-1996038435-A1 | DOPAMINE AGONISTS | ABBOTT LABORATORIES (US) | 1996-12-05 | — | — | WO | disclosed |
| EP-0474767-B1 | DOPAMINE AGONISTS | ABBOTT LAB (US) | 1996-02-21 | — | — | EP | disclosed |
| EP-0474767-A4 | DOPAMINE AGONISTS | — | 1992-07-08 | — | — | EP | disclosed |
| EP-0474767-A1 | DOPAMINE AGONISTS. | ABBOTT LAB (US) | 1992-03-18 | — | — | EP | disclosed |