Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7359213 | 0.93 | EDNRB (0.67) | EDNRBEDNRA | |
| SCHEMBL29551210 | 0.93 | EDNRB (0.67) | EDNRBEDNRA | |
| SCHEMBL7433861 | 0.93 | EDNRB (0.66) | EDNRBEDNRA | |
| SCHEMBL7445306 | 0.92 | EDNRB (0.68) | EDNRBEDNRA | |
| SCHEMBL7442871 | 0.89 | EDNRB (0.58) | EDNRBEDNRA | |
| SCHEMBL7446238 | 0.89 | EDNRB (0.68) | EDNRBEDNRA | |
| SCHEMBL7445499 | 0.87 | EDNRB (0.56) | EDNRBEDNRA | |
| SCHEMBL7450549 | 0.85 | EDNRB (0.69) | EDNRBEDNRA | |
| SCHEMBL7446545 | 0.82 | EDNRB (0.59) | EDNRBEDNRA | |
| SCHEMBL7444237 | 0.81 | EDNRB (0.63) | EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0753004-A1 | ANTAGONISTS OF ENDOTHELIN RECEPTORS | Japat Ltd (CH) | 1997-01-15 | — | — | EP | claimed |
| WO-1995026360-A1 | ANTAGONISTS OF ENDOTHELIN RECEPTORS | JAPAT LTD. (CH) | 1995-10-05 | — | — | WO | claimed |
| US-5703106-A | TREATING VARIOUS CARDIOVASCULAR, UROGENITAL, BRAIN DISORDERS | JAPAT LTD. (CH) | 1997-12-30 | — | — | US | disclosed |
| EP-0753004-A1 | ANTAGONISTS OF ENDOTHELIN RECEPTORS | Japat Ltd (CH) | 1997-01-15 | — | — | EP | disclosed |
| WO-1995026360-A1 | ANTAGONISTS OF ENDOTHELIN RECEPTORS | JAPAT LTD. (CH) | 1995-10-05 | — | — | WO | disclosed |