Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | RARG | P13631 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7426427 | 1.00 | MME (0.42) | MMEANPEPGAACYP3A4CYP2C19 | |
| SCHEMBL7440460 | 1.00 | MME (0.42) | MMEANPEPGAACYP3A4CYP2C19 | |
| SCHEMBL7441684 | 0.89 | MME (0.54) | MMEANPEPCYP3A4CYP2C19LTA4H | |
| SCHEMBL7446640 | 0.89 | MME (0.54) | MMEANPEPCYP3A4CYP2C19LTA4H | |
| SCHEMBL489493 | 0.87 | MME (0.46) | MMEANPEPGAACYP3A4CYP2C19 | |
| SCHEMBL29977652 | 0.87 | MME (0.46) | MMEANPEPGAACYP3A4CYP2C19 | |
| SCHEMBL29436985 | 0.87 | MME (0.46) | MMEANPEPGAACYP3A4CYP2C19 | |
| SCHEMBL29436986 | 0.87 | MME (0.46) | MMEANPEPGAACYP3A4CYP2C19 | |
| SCHEMBL389352 | 0.87 | MME (0.46) | MMEANPEPGAACYP3A4CYP2C19 | |
| SCHEMBL389351 | 0.87 | MME (0.46) | MMEANPEPGAACYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5262436-A | Administering; enzyme inhibitor | SCHERING CORPORATION (US) | 1993-11-16 | — | — | US | disclosed |
| US-5061710-A | Atrial natriuretic factors | SCHERING CORPORATION (US) | 1991-10-29 | — | — | US | disclosed |
| US-4929641-A | DIURETICS, ANGIOTENSIN CONVERTING ENZYMES | SCHERING CORPORATION (US) | 1990-05-29 | — | — | US | disclosed |