Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 4/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 4/20 | 0.40 |
| ▸ | FAAH | O00519 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27590207 | 0.84 | CYP2C19 (0.38) | MAPTLMNAL3MBTL1SIGMAR1 | |
| SCHEMBL7201704 | 0.82 | CYP2C19 (0.42) | MAPTRXFP1 | |
| SCHEMBL9296370 | 0.81 | GRM2 (0.47) | LTB4RGRM2GRM3MAPTRXFP1 | |
| SCHEMBL7077556 | 0.80 | CYP2C19 (0.42) | MAPTLMNASIGMAR1 | |
| SCHEMBL6704312 | 0.80 | CYP2C19 (0.42) | MAPT | |
| SCHEMBL28356647 | 0.80 | CYP2C19 (0.42) | MAPT | |
| SCHEMBL5393356 | 0.80 | GRM2 (0.54) | LTB4RGRM2GRM3MAPTRXFP1 | |
| SCHEMBL9543954 | 0.79 | CYP2C19 (0.45) | MAPT | |
| SCHEMBL28750864 | 0.79 | CYP2C19 (0.41) | MAPTLMNASIGMAR1 | |
| Ammonia Solution, Strong SCHEMBL28873439 | 0.79 | CYP2C19 (0.41) | MAPTPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876353-A1 | RETROVIRAL PROTEASE INHIBITING COMPOUNDS | Abbott Laboratories (US) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997021683-A1 | RETROVIRAL PROTEASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1997-06-19 | — | — | WO | disclosed |