SCHEMBL7445835

SCHEMBL7445835

CO[Si](CC1CCCCC1)(CC1CCCCC1)OC

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.36
ALDH1A1 P00352 1/20 0.32
ACHE P22303 1/20 0.31
CHRM5 P08912 2/20 0.31
ADRA2C P18825 1/20 0.31
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
CHRM1 P11229 1/20 0.31
SIGMAR1 Q99720 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30189486 1.00 CYP1A2 (0.36) CYP1A2ALDH1A1ACHECHRM5ADRA2C
SCHEMBL30189746 1.00 CYP1A2 (0.36) CYP1A2ALDH1A1ACHECHRM5ADRA2C
SCHEMBL7643953 1.00 CYP1A2 (0.36) CYP1A2ALDH1A1ACHECHRM5ADRA2C
SCHEMBL30189547 1.00 CYP1A2 (0.36) CYP1A2ALDH1A1ACHECHRM5ADRA2C
SCHEMBL30189693 0.98 CYP1A2 (0.34) CYP1A2ALDH1A1ACHECHRM5ADRA2C
SCHEMBL30189572 0.98 CYP1A2 (0.34) CYP1A2ALDH1A1ACHECHRM5ADRA2C
SCHEMBL30189645 0.98 CYP1A2 (0.34) CYP1A2ALDH1A1ACHECHRM5ADRA2C
SCHEMBL30189652 0.98 CYP1A2 (0.34) CYP1A2ALDH1A1ACHECHRM5ADRA2C
SCHEMBL7453882 0.97 CYP1A2 (0.32) CYP1A2ALDH1A1
SCHEMBL30189623 0.95 CYP1A2 (0.31) CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6469112-B2 SOLID TITANIUM CATALYST COMPONENT; AN ORGANOALUMINUM COMPOUND; AND AN ORGANOSILICON COMPOUND COMPRISING AT LEAST ONE (CYCLOALKYL)METHYL GROUP; MAKING HIGH XYLENE SOLUBLE POLYOLEFINS WITH CATALYTIC EFFICIENCY ENGELHARD CORPORATION 2002-10-22 US claimed
US-20020028893-A1 (Cycloalkyl) methyl silanes as external donors for polyolefin catalysts W. R. GRACE & CO.-CONN. 2002-03-07 US claimed
US-6469112-B2 SOLID TITANIUM CATALYST COMPONENT; AN ORGANOALUMINUM COMPOUND; AND AN ORGANOSILICON COMPOUND COMPRISING AT LEAST ONE (CYCLOALKYL)METHYL GROUP; MAKING HIGH XYLENE SOLUBLE POLYOLEFINS WITH CATALYTIC EFFICIENCY ENGELHARD CORPORATION 2002-10-22 US disclosed
EP-0693524-B1 Polypropylene resin and film prepared therefrom IDEMITSU PETROCHEMICAL CO (JP) 1998-06-10 EP disclosed
EP-0693524-A1 Polypropylene resin and film prepared therefrom IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1996-01-24 EP disclosed