Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 12/20 | 0.62 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7452046 | 0.94 | F2 (0.68) | F2MCHR1KDM4EMAPTSIGMAR1 | |
| SCHEMBL7446550 | 0.90 | F2 (0.64) | F2 | |
| SCHEMBL7446154 | 0.83 | F2 (0.70) | F2 | |
| SCHEMBL6595508 | 0.83 | F2 (0.91) | F2 | |
| SCHEMBL7452879 | 0.81 | F2 (0.52) | F2 | |
| SCHEMBL7346685 | 0.81 | F2 (0.62) | F2 | |
| SCHEMBL7819922 | 0.81 | MCHR1 (0.56) | F2MCHR1KDM4E | |
| SCHEMBL7438768 | 0.81 | F2 (0.71) | F2 | |
| SCHEMBL7440889 | 0.80 | HRH3 (0.58) | F2 | |
| SCHEMBL7452057 | 0.79 | HRH3 (0.54) | F2KDM4EMAPTSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863755-A4 | ANTITHROMBOTIC DIAMINES | LILLY CO ELI (US) | 1999-01-20 | — | — | EP | disclosed |
| EP-0863755-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997025033-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |