Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 16/20 | 0.63 |
| ▸ | CTRC | Q99895 | 5/20 | 0.63 |
| ▸ | PRSS2 | P07478 | 5/20 | 0.62 |
| ▸ | CA12 | O43570 | 4/20 | 0.52 |
| ▸ | CA1 | P00915 | 4/20 | 0.52 |
| ▸ | CA2 | P00918 | 4/20 | 0.52 |
| ▸ | CA9 | Q16790 | 4/20 | 0.52 |
| ▸ | F10 | P00742 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7446027 | 0.99 | F2 (0.61) | F2CTRCPRSS2CA12CA1 | |
| SCHEMBL7442943 | 0.96 | F2 (0.62) | F2CTRCPRSS2CA12CA1 | |
| Hydrochloric Acid SCHEMBL7450506 | 0.84 | F2 (0.75) | F2CTRCPRSS2F10 | |
| SCHEMBL5674291 | 0.79 | F2 (0.74) | F2CTRCPRSS2F10 | |
| Acetic Acid SCHEMBL7603833 | 0.79 | F2 (0.71) | F2CTRCPRSS2F10 | |
| SCHEMBL8158052 | 0.79 | F2 (0.73) | F2CTRCPRSS2F10 | |
| SCHEMBL3642918 | 0.78 | F2 (0.70) | F2CTRCPRSS2F10 | |
| SCHEMBL3647138 | 0.77 | F2 (0.71) | F2CTRCPRSS2F10 | |
| SCHEMBL6553417 | 0.77 | F2 (0.68) | F2CTRCPRSS2F10 | |
| SCHEMBL6750719 | 0.76 | F2 (0.73) | F2CTRCPRSS2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0859607-B1 | GUANIDINO PROTEASE INHIBITORS | DIMENSIONAL PHARM INC (US) | 2002-12-18 | — | — | EP | disclosed |
| EP-0859607-A4 | GUANIDINO PROTEASE INHIBITORS | DIMENSIONAL PHARM INC (US) | 1999-05-06 | — | — | EP | disclosed |
| EP-0859607-A1 | GUANIDINO PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1998-08-26 | — | — | EP | disclosed |
| WO-1997011693-A1 | GUANIDINO PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1997-04-03 | — | — | WO | disclosed |