Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 5/20 | 0.35 |
| ▸ | REN | P00797 | 3/20 | 0.32 |
| ▸ | F2 | P00734 | 5/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.31 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6374495 | 0.90 | BIRC2 (0.33) | ACERENF2OPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL7417456 | 0.89 | BIRC2 (0.32) | ACERENF2OPRM1OPRK1 | |
| SCHEMBL9240904 | 0.88 | F2 (0.33) | ACERENF2OPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL7415560 | 0.88 | PREP (0.36) | F2OPRM1OPRK1 | |
| Sulfuric Acid SCHEMBL6373694 | 0.87 | BIRC2 (0.31) | F2 | |
| Sulfurous Acid SCHEMBL7414609 | 0.87 | BIRC2 (0.31) | ACEF2 | |
| SCHEMBL7444970 | 0.86 | F2 (0.32) | F2 | |
| Hydrochloric Acid SCHEMBL7415745 | 0.86 | F2 (0.31) | F2 | |
| Sulfurous Acid SCHEMBL8644931 | 0.85 | BIRC2 (0.30) | — | |
| Hydrochloric Acid SCHEMBL7410940 | 0.84 | ACE (0.33) | ACEF2OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0748333-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2000-05-10 | — | — | EP | claimed |
| US-5602101-A | THROMBIN INHIBITORS, ANTICOAGULANTS | ELI LILLY AND COMPANY (US) | 1997-02-11 | — | — | US | claimed |
| EP-0748333-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1996-12-18 | — | — | EP | claimed |
| WO-1995023809-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1995-09-08 | — | — | WO | claimed |