Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 20/20 | 0.64 |
| ▸ | PDE4A | P27815 | 19/20 | 0.64 |
| ▸ | PDE4C | Q08493 | 19/20 | 0.64 |
| ▸ | PDE4D | Q08499 | 19/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9244307 | 0.81 | PDE4B (0.81) | PDE4BPDE4APDE4CPDE4D | |
| Butane SCHEMBL9241989 | 0.80 | PDE4B (0.94) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL8676636 | 0.78 | PDE4B (1.00) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7418485 | 0.78 | PDE4B (1.00) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7422177 | 0.78 | PDE4B (1.00) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7423821 | 0.77 | PDE4B (1.00) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL8568210 | 0.76 | PDE4A (0.79) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL5495203 | 0.76 | PDE4A (1.00) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6172991 | 0.76 | PDE4B (1.00) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7416733 | 0.76 | PDE4B (1.00) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799176-A4 | 4,4-(DISUBSTITUTED)CYCLOHEXAN-1-ONE DIMERS AND RELATED COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 1998-03-25 | — | — | EP | disclosed |
| EP-0799176-A1 | 4,4-(DISUBSTITUTED)CYCLOHEXAN-1-ONE DIMERS AND RELATED COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-10-08 | — | — | EP | disclosed |
| WO-1996020153-A1 | 4,4-(DISUBSTITUTED)CYCLOHEXAN-1-ONE DIMERS AND RELATED COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-07-04 | — | — | WO | disclosed |