SCHEMBL7447123

SCHEMBL7447123

C=CC(=O)NC(C)CC.[NaH]

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.58
MMP1 P03956 1/20 0.45
MMP2 P08253 1/20 0.45
MMP3 P08254 1/20 0.45
ACACB O00763 2/20 0.42
PKM P14618 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TAS1R3 Q7RTX0 1/20 0.41
TAS1R1 Q7RTX1 1/20 0.41
ALDH1A1 P00352 4/20 0.39
MAPK1 P28482 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
ZDHHC20 Q5W0Z9 1/20 0.38
ZDHHC2 Q9UIJ5 1/20 0.38
KMT2A Q03164 2/20 0.38
EPHX1 P07099 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL319728 0.98
SCHEMBL8401460 0.98
SCHEMBL1315706 0.98
Ammonia Solution, Strong SCHEMBL28050078 0.96 TSHR (0.58) TSHRMMP1MMP2MMP3ACACB
SCHEMBL14344159 0.96 TSHR (0.58) TSHRMMP1MMP2MMP3ACACB
Hydrogen Sulfide SCHEMBL28195736 0.96 TSHR (0.58) TSHRMMP1MMP2MMP3ACACB
Dimethylamine SCHEMBL28317954 0.94 TSHR (0.56) TSHRMMP1MMP2MMP3ACACB
Acetone SCHEMBL28215913 0.94 TSHR (0.56) TSHRMMP1MMP2MMP3ACACB
Acrylamide SCHEMBL7164013 0.92 TSHR (0.50) TSHRMMP1MMP2MMP3ACACB
Phosphonic Acid SCHEMBL18424925 0.90 TSHR (0.52) TSHRMMP1MMP2MMP3ACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4224210-A Fiber from acrylonitrile copolymers having reduced inflammability, compositions and processes for manufacturing the same SNIA VISCOSA SOCIETA' NAZIONALE INDUSTRIA APPLICAZIONI VISCOSA S.P.A. (IT) 1980-09-23 US claimed
US-4223108-A ACRYLONITRILE-VINYLIDENE CHLORIDE COPOLYMER, ACRYLONITRILE COPOLYMER WITH ACRYLAMIDO-ALKANESULFONIC ACID SNIA VISCOSA SOCIETA' NAZIONALE INDUSTRIA APPLICAZIONI VISCOSA S.P.A. (IT) 1980-09-16 US claimed
US-6468710-B1 HYDRAZINE NUCLEATING AGENT, PERFLUOROALKYL SURFACTANT FUJI PHOTO FILM CO., LTD. (JP) 2002-10-22 US disclosed
EP-0832854-A1 Sulfobetaine-containing polymers and their utility as calcium carbonate scale inhibitors NALCO CHEMICAL COMPANY (US) 1998-04-01 EP disclosed
EP-0457356-B1 Process for preparing acrylic polymers in suspension ATOCHEM ELF ITALIA (IT) 1995-09-13 EP disclosed
US-5344901-A Emulsion polymerization in presence of sulfoacrylamide salt polymer ATOCHEM INDUSTRIALE S.R.L. (IT) 1994-09-06 US disclosed
EP-0457356-A2 Process for preparing acrylic polymers in suspension ELF ATOCHEM ITALIA S.r.l. (IT) 1991-11-21 EP disclosed
EP-0152814-A2 Hydrosoluble polymers and their use as additives in drilling fluids Wolff Walsrode Aktiengesellschaft (DE) 1985-08-28 EP disclosed
US-4287148-A FROM A MIXTURE OF A COPOLYMER OF ACRYLONITRILE WITH A SULFONATED ACRYLIC AMIDE, AND A COPOLYMER OF ACRYLONITRILE WITH VINYLIDENE CHLORIDE SNIA VISCOSA (IT) 1981-09-01 US disclosed
US-4224210-A Fiber from acrylonitrile copolymers having reduced inflammability, compositions and processes for manufacturing the same SNIA VISCOSA SOCIETA' NAZIONALE INDUSTRIA APPLICAZIONI VISCOSA S.P.A. (IT) 1980-09-23 US disclosed
US-4224210-A Fiber from acrylonitrile copolymers having reduced inflammability, compositions and processes for manufacturing the same SNIA VISCOSA SOCIETA' NAZIONALE INDUSTRIA APPLICAZIONI VISCOSA S.P.A. (IT) 1980-09-23 US disclosed
US-4223108-A ACRYLONITRILE-VINYLIDENE CHLORIDE COPOLYMER, ACRYLONITRILE COPOLYMER WITH ACRYLAMIDO-ALKANESULFONIC ACID SNIA VISCOSA SOCIETA' NAZIONALE INDUSTRIA APPLICAZIONI VISCOSA S.P.A. (IT) 1980-09-16 US disclosed