Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | RAB9A | P51151 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.61 |
| ▸ | MMP13 | P45452 | 8/20 | 0.60 |
| ▸ | MMP2 | P08253 | 6/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | MMP14 | P50281 | 4/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7451945 | 0.88 | KDM4E (0.62) | KDM4EALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL829242 | 0.86 | KDM4E (0.76) | KDM4EALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL28004667 | 0.85 | KDM4E (0.60) | KDM4EALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL13174359 | 0.84 | KDM4E (0.72) | KDM4EALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL7447135 | 0.83 | KDM4E (0.70) | KDM4EALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL7365199 | 0.83 | KDM4E (0.70) | KDM4EALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL3560424 | 0.82 | KDM4E (0.68) | KDM4EALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL1420412 | 0.82 | KDM4E (0.68) | KDM4EALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL12042728 | 0.81 | KDM4E (0.64) | KDM4EALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL10395119 | 0.81 | KDM4E (0.67) | KDM4EALDH1A1HPGDRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918768-A1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C Research Laboratories (KR) | 1999-06-02 | — | — | EP | disclosed |
| WO-1997045424-A1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C RESEARCH LABORATORIES (KR) | 1997-12-04 | — | — | WO | disclosed |