Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.51 |
| ▸ | ALPI | P09923 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | XIAP | P98170 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | MC4R | P32245 | 2/20 | 0.43 |
| ▸ | MC3R | P41968 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TPH1 | P17752 | 2/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.42 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | MC5R | P33032 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7445543 | 0.85 | SLC7A5 (0.50) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL7448659 | 0.82 | SLC7A5 (0.47) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL7453774 | 0.81 | SLC7A5 (0.46) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL28222736 | 0.81 | ANPEP (0.54) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL8016051 | 0.81 | ANPEP (0.54) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine SCHEMBL7525344 | 0.81 | SLC7A5 (0.79) | SLC7A5ALPIPKMPTGS1XIAP | |
| Dl-Phenylalanine SCHEMBL7525343 | 0.81 | SLC7A5 (0.79) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL10584413 | 0.78 | SLC7A5 (0.62) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL7531787 | 0.76 | ALPI (0.50) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL7531784 | 0.76 | ALPI (0.50) | SLC7A5ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221888-B1 | ANTIHISTAMINE, ANTIINFLAMMATORY AGENT, AUTOIMMUNE DISEASE, RHEUMATIC DISORDERS | MERCK & CO., INC. | 2001-04-24 | — | — | US | disclosed |
| EP-0998282-A4 | SULFONAMIDES AS CELL ADHESION INHIBITORS | MERCK & CO INC (US) | 2000-08-30 | — | — | EP | disclosed |
| EP-0998282-A1 | SULFONAMIDES AS CELL ADHESION INHIBITORS | Merck & Co., Inc. (a New Jersey corp.) (US) | 2000-05-10 | — | — | EP | disclosed |
| WO-1998053818-A1 | SULFONAMIDES AS CELL ADHESION INHIBITORS | MERCK & CO., INC. (US) | 1998-12-03 | — | — | WO | disclosed |