Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | UBE2M | P61081 | 1/20 | 0.31 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7436547 | 0.89 | DPP4 (0.37) | DPP4 | |
| SCHEMBL7438702 | 0.87 | DPP4 (0.42) | DPP4TSHRSMN1; SMN2UBE2MDCUN1D1 | |
| SCHEMBL7449543 | 0.82 | DPP4 (0.38) | DPP4TSHRSMN1; SMN2UBE2MDCUN1D1 | |
| SCHEMBL7438261 | 0.82 | DPP4 (0.34) | DPP4UBE2MDCUN1D1 | |
| SCHEMBL7436891 | 0.82 | DPP4 (0.40) | DPP4TSHRSMN1; SMN2UBE2MDCUN1D1 | |
| SCHEMBL7441498 | 0.81 | DPP4 (0.37) | DPP4UBE2MDCUN1D1 | |
| SCHEMBL7444456 | 0.80 | DPP4 (0.38) | DPP4TSHRSMN1; SMN2UBE2MDCUN1D1 | |
| SCHEMBL7448323 | 0.80 | DPP4 (0.38) | DPP4UBE2MDCUN1D1 | |
| SCHEMBL7447045 | 0.79 | DPP4 (0.37) | DPP4UBE2MDCUN1D1 | |
| SCHEMBL7443560 | 0.79 | DPP4 (0.36) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0628559-B1 | Pyrimidine compounds and their use as pharmaceuticals | BEIERSDORF LILLY GMBH (DE) | 2002-04-03 | — | — | EP | disclosed |
| US-5602136-A | Pyrimidine compounds and their use as pharmaceuticals | BEIERSDORF-LILLY GMBH (DE) | 1997-02-11 | — | — | US | disclosed |
| US-5602137-A | Pyrimidine compounds and their use as pharmaceuticals | BEIERSDORF-LILLY GMBH (DE) | 1997-02-11 | — | — | US | disclosed |
| US-5571813-A | Fused pyrimidine compounds and their use as pharmaceuticals | BEIERSDORF-LILLY GMBH (DE) | 1996-11-05 | — | — | US | disclosed |
| EP-0628559-A1 | Pyrimidine compounds and their use as pharmaceuticals | Beiersdorf-Lilly GmbH (DE) | 1994-12-14 | — | — | EP | disclosed |