Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14000783 | 0.89 | — | — | |
| SCHEMBL147241 | 0.89 | — | — | |
| SCHEMBL5791362 | 0.89 | — | — | |
| Methane SCHEMBL7004649 | 0.86 | MAPK1 (0.44) | MAPK1TSHRLMNA | |
| Propane SCHEMBL20677049 | 0.86 | MAPK1 (0.44) | MAPK1TSHRLMNA | |
| SCHEMBL9543323 | 0.86 | MAPK1 (0.44) | MAPK1TSHRLMNA | |
| Ethane SCHEMBL7007928 | 0.86 | MAPK1 (0.44) | MAPK1TSHRLMNA | |
| Phosphine SCHEMBL21561433 | 0.86 | MAPK1 (0.44) | MAPK1TSHRLMNA | |
| Potassium SCHEMBL9541959 | 0.86 | MAPK1 (0.44) | MAPK1TSHRLMNA | |
| Ammonia Solution, Strong SCHEMBL1007891 | 0.86 | MAPK1 (0.44) | MAPK1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977743-A1 | PROTEASE INHIBITORS | Smithkline Beecham (US) | 2000-02-09 | — | — | EP | disclosed |
| WO-1998049152-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-11-05 | — | — | WO | disclosed |