Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.41 |
| ▸ | FPR2 | P25090 | 2/20 | 0.40 |
| ▸ | FPR1 | P21462 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 11/20 | 0.39 |
| ▸ | FEN1 | P39748 | 11/20 | 0.39 |
| ▸ | NAMPT | P43490 | 3/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7456108 | 0.84 | F10 (0.51) | F10F2 | |
| SCHEMBL7451701 | 0.79 | F10 (0.43) | F10FPR2FPR1ALOX5APFEN1 | |
| SCHEMBL6628707 | 0.78 | F10 (0.59) | F10USP30ALOX5APFEN1NAMPT | |
| SCHEMBL6162229 | 0.78 | SCN3A (0.44) | F10FPR2FPR1USP30ALOX5AP | |
| SCHEMBL6163283 | 0.78 | SCN3A (0.44) | F10FPR2FPR1USP30ALOX5AP | |
| SCHEMBL7084412 | 0.76 | F10 (0.45) | F10FPR2FPR1USP30ALOX5AP | |
| SCHEMBL6166616 | 0.76 | F10 (0.52) | F10ALOX5APFEN1NAMPT | |
| SCHEMBL7081191 | 0.75 | F10 (0.41) | F10FPR2FPR1USP30ALOX5AP | |
| SCHEMBL7078594 | 0.75 | F10 (0.41) | F10FPR2FPR1USP30ALOX5AP | |
| SCHEMBL7451707 | 0.74 | F10 (0.53) | F10ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189879-A1 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 2002-03-27 | — | — | EP | disclosed |
| WO-2000071512-A1 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 2000-11-30 | — | — | WO | disclosed |